Stanford School of Medicine
Endocrinology and Diabetes– In the Department of Pediatrics

Clinical Study Details

Title

Neuropsychological and Neuroanatomical Studies in Young Children

Description

This study is being conducted to see if type 1 diabetes has any affect on learning, behavior, and development in young children and whether there are associated changes on their MRI scan. In this pilot study approximately 10-20 children between the ages of 3 and 10 years old with type 1 diabetes will have neuropsychological testing and a nonsedated MRI scan of the head performed every year for three years. We will compare this to a control group of 10 children between the ages of 3 and 10 years without type 1 diabetes. The control subjects will have neuropsychological testing and a nonsedated MRI scan of the head once. The children with type 1 diabetes will not have any changes made to their current diabetes regimen.

Eligibility

You (or your child) must meet the following inclusion criteria:

1) Be between the ages of 3 and 10 years.
2) Have been diagnosed with type 1 diabetes for at least 6 months.
3) Do not have plans to move out of the area within the next 36 months.If the interested participant has any history of head trauma with any loss of consciousness, cystic fibrosis, prematurity (born less than 30 weeks gestation), significant developmental delay, neurologic disease independent of diabetes, or medical contraindication to MRI procedure, they are not eligible to participate in this study.

Procedures

One visit for 3-4 hours will take place at Stanford Medical Center to complete the neuropsychological testing and to become familiar with the MRI scanner. Subjects who need to become more familiar with the MRI scanner will review a video tape at home. One visit for 1-2 hours will take place at Lucile Packard Children's Hospital to have the MRI completed. Subjects with type 1 diabetes will have the neuropsychological testing and MRI scan repeated again in 12 and 24 months from the time of the intial testing and scan.

Contact

If you are interested in participating in this study and you meet the inclusion criteria, please contact Dr. Tandy Aye by email at taye@stanford.edu or by phone at (650) 723-5791.

Please review the consent and assent forms for more information.

 

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